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Avian influenza A: an avian influenza virus from low pathogenic to highly pathogenic

William J. Liu, Haixia Xiao, Lianpan Dai, Di Liu, Jianjun Chen, Xiaopeng Qi, Yuhai Bi, Yi Shi, George F. Gao, Yingxia Liu

Frontiers of Medicine 2021, Volume 15, Issue 4,   Pages 507-527 doi: 10.1007/s11684-020-0814-5

Abstract: The avian influenza A (H7N9) virus is a zoonotic virus that is closely associated with live poultry marketsFive waves of the H7N9 influenza epidemic occurred in China between March 2013 and September 2017.H7N9 with low-pathogenicity dominated in the first four waves, whereas highly pathogenic H7N9 influenzaand other countries responded quickly, controlled the epidemic well thus far, and characterized the virus

Keywords： H7N9     HPAIV     epidemiology     clinical features     pathogenesis     hemagglutinin     immunity     vaccine    

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Endemicity of H9N2 and H5N1 avian influenza viruses in poultry in China poses a serious threat to poultry

Jiao HU,Xiufan LIU

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 1,   Pages 11-24 doi: 10.15302/J-FASE-2016092

Abstract: The H9N2 and H5N1 avian influenza viruses (AIVs) have been circulating in poultry in China and becomeendemicity makes them actively involved in the emergence of the novel lineages of other subtypes of influenzaviruses, such as the well-known viruses of the highly pathogenic avian influenza (HPAI) H5N2 and the

Keywords： avian influenza virus     H9N2     H5N1     novel viruses     public health    

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The first avian influenza A (H7N9) viral infection in humans in Zhejiang Province, China: a death report

Enfu Chen, Fenjuan Wang, Huakun Lv, Yanjun Zhang, Hua Ding, Shelan Liu, Jian Cai, Li Xie, Xiaoping Xu, Chengliang Chai, Haiyan Mao, Jimin Sun, Junfen Lin, Zhao Yu, Lianhong Li, Zhiping Chen, Shichang Xia

Frontiers of Medicine 2013, Volume 7, Issue 3,   Pages 333-344 doi: 10.1007/s11684-013-0275-1

Abstract:

This study reports the first death caused by a novel avian influenza A (H7N9) virus in Zhejiang ProvinceThis H7N9 virus from Zhejiang is highly similar to isolates obtained from Shanghai, Jiangsu, Anhui, etcAnalysis of hemagglutinin, neuramidinase, and matrix genes indicated that the isolates share the same avianinfluenza A (H7N9).Person-to-person transmission of the H7N9 virus was not detected among close contacts, but such transmission

Keywords： avian influenza A (H7N9) virus     epidemiology     contacts     person-to-person transmission    

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Assessment of vaccination strategies against highly pathogenic avian influenza in China

Honglei SUN,Jinhua LIU

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 4,   Pages 277-281 doi: 10.15302/J-FASE-2014036

Abstract: Vaccination for highly pathogenic avian influenza (HPAI) has been implemented in China for a decade,however, the virus is still present in poultry.

Keywords： highly pathogenic avian influenza     vaccine     vaccination     control    

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Research progress on human infection with avian influenza H7N9

Xiaoxin Wu, Lanlan Xiao, Lanjuan Li

Frontiers of Medicine 2020, Volume 14, Issue 1,   Pages 8-20 doi: 10.1007/s11684-020-0739-z

Abstract: Meanwhile, the H7N9 virus continues to accumulate mutations, and its affinity for the human respiratorythe past 6 years, we have accumulated rich experience in dealing with H7N9, especially in terms of viruswe reviewed the clinical and epidemiological characteristics of H7N9, the key gene mutations of the virus, and H7N9 vaccine, thus providing a scientific basis for further monitoring and prevention of H7N9 influenza

Keywords： H7N9     pandemic     epidemiology     mutations     vaccine     influenza    

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Recent advances in “universal” influenza virus antibodies: the rise of a hidden trimeric interface in

Yulu Wang, Dan Hu, Yanling Wu, Tianlei Ying

Frontiers of Medicine 2020, Volume 14, Issue 2,   Pages 149-159 doi: 10.1007/s11684-020-0764-y

Abstract: Influenza causes seasonal outbreaks yearly and unpredictable pandemics with high morbidity and mortalityDespite significant efforts to address influenza, it remains a major threat to human public health.virus strains and the rapid emergence of drug-resistant variants.Moreover, designing a universal influenza vaccine that is sufficiently immunogenic to induce universalvirus to promote the development of universal anti-influenza antibodies or vaccines and extend the discovery

Keywords： influenza virus     neutralizing antibody     hemagglutinin     globular head region     trimeric interface    

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Universal influenza virus vaccines: what can we learn from the human immune response following exposure

Daniel Stadlbauer, Raffael Nachbagauer, Philip Meade, Florian Krammer

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 471-479 doi: 10.1007/s11684-017-0602-z

Abstract:

Several universal influenza virus vaccine candidates based on eliciting antibodies against the hemagglutininwhat is known about the human humoral immune response to vaccination and infection with H7 subtype influenzaunderstanding of this phenomenon and the underlying mechanisms might help to develop future universal influenzavirus vaccine candidates.

Keywords： universal influenza virus vaccine     hemagglutinin stalk     H7N9    

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Seroprevalence of influenza viruses in Shandong, Northern China during the COVID-19 pandemic

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 984-990 doi: 10.1007/s11684-022-0930-5

Abstract: control the spread of the coronavirus disease 2019 (COVID-19), resulting in a worldwide decline in influenzaHowever, the influenza risk in China warrants cautious assessment.Hemagglutination inhibition was performed to test antibodies against four influenza vaccine strains.A combination of descriptive and meta-analyses was adopted to compare the seroprevalence of influenzaIncreasing vaccination rates and maintaining NPIs are recommended to prevent an elevated influenza risk

Keywords： influenza virus     seroprevalence     antibody     COVID-19     cross-sectional study    

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Pathogenesis of pandemic H1N1 2009 influenza virus infection and the implication on management

Kelvin Kai-Wang TO FRCPath, Iris Wai-Sum LI FRCP, Ivan Fan-Ngai HUNG FRCP, Vincent Chi-Chung CHENG FRCPath, Kwok-Yung YUEN MD,

Frontiers of Medicine 2010, Volume 4, Issue 2,   Pages 147-156 doi: 10.1007/s11684-010-0030-9

Abstract: The pandemic H1N1 2009 influenza virus has caused the first influenza pandemic of the 21st century, leading

Keywords： influenza A virus     H1N1 subtype     pandemic     pathogenesis     virulence factors     immunity     management     antiviral    

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Innate and adaptive T cells in influenza disease

Simone Nüssing, Sneha Sant, Marios Koutsakos, Kanta Subbarao, Thi H.O. Nguyen, Katherine Kedzierska

Frontiers of Medicine 2018, Volume 12, Issue 1,   Pages 34-47 doi: 10.1007/s11684-017-0606-8

Abstract:

Influenza is a major global health problem, causing infections of the respiratory tract, often leadinglast seven decades, vaccination strategies have been utilized to protect people from complications of influenzastrain-specific antibody responses, they fail to generate cross-protection against seasonal, pandemic and avianMoreover, vaccines designed to generate influenza-specific T-cell responses are yet to be optimized.We summarize the current knowledge on influenza-specific innate MAIT and gd T cells as well as adaptive

Keywords： influenza     innate T cells     CD4+ and CD8+ T cells     vaccination    

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Compiling of comprehensive data of human infections with novel influenza A (H7N9) virus

Ying Wu, George F. Gao

Frontiers of Medicine 2013, Volume 7, Issue 3,   Pages 275-276 doi: 10.1007/s11684-013-0285-z

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Global influenza surveillancewith Laplacianmultidimensional scaling

Xi-chuan ZHOU,Fang TANG,Qin LI,Sheng-dong HU,Guo-jun LI,Yun-jian JIA,Xin-ke LI,Yu-jie FENG

Frontiers of Information Technology & Electronic Engineering 2016, Volume 17, Issue 5,   Pages 413-421 doi: 10.1631/FITEE.1500356

Abstract: The Global Influenza Surveillance Network is crucial for monitoring epidemic risk in participating countriesMotivated by the observation that countries in the same influenza transmission zone divided by the WorldHealth Organization had similar transmission patterns, we propose to estimate the influenza epidemicExperiments show that the risk estimates are highly correlated with the actual influenza morbidity trendsThe proposed method may provide the much-needed capability to detect, assess, and notify potential influenza

Keywords： Surveillance gap     Influenza     Spatial-transmission model    

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Removal of virus aerosols by the combination of filtration and UV-C irradiation

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 3, doi: 10.1007/s11783-023-1627-y

Abstract:

● The removal of virus aerosols by filtration and UV-C irradiation

Keywords： Filtration system     UV-C irradiation     Virus aerosol     Public health     COVID-19    

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Critical roles of chemokines and cytokines in antiviral innate immune responses during rabies virus infection

Ying HUANG, Clement Wesley GNANADURAI, Zhenfang FU

Frontiers of Agricultural Science and Engineering 2017, Volume 4, Issue 3,   Pages 260-267 doi: 10.15302/J-FASE-2016116

Abstract: pro-inflammatory chemokines and cytokines have a critical function in the innate immune responses against virusThe ability of a rabies virus (RABV) to induce the expression of chemokines and cytokines can lead to

Keywords： antiviral     blood brain barrier     chemokines and cytokines     innate immunity     rabies virus    

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Immunological and virological characteristics of human immunodeficiency virus type 1 superinfection:

Yang Gao, Wen Tian, Xiaoxu Han, Feng Gao

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 480-489 doi: 10.1007/s11684-017-0594-8

Abstract:

Superinfection is frequently detected among individuals infected by human immunodeficiency virus type

Keywords： human immunodeficiency virus type I     superinfection     incidence     immune response    

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Title Author Date Type Operation

Avian influenza A: an avian influenza virus from low pathogenic to highly pathogenic

William J. Liu, Haixia Xiao, Lianpan Dai, Di Liu, Jianjun Chen, Xiaopeng Qi, Yuhai Bi, Yi Shi, George F. Gao, Yingxia Liu

Journal Article

Endemicity of H9N2 and H5N1 avian influenza viruses in poultry in China poses a serious threat to poultry

Jiao HU,Xiufan LIU

Journal Article

The first avian influenza A (H7N9) viral infection in humans in Zhejiang Province, China: a death report

Enfu Chen, Fenjuan Wang, Huakun Lv, Yanjun Zhang, Hua Ding, Shelan Liu, Jian Cai, Li Xie, Xiaoping Xu, Chengliang Chai, Haiyan Mao, Jimin Sun, Junfen Lin, Zhao Yu, Lianhong Li, Zhiping Chen, Shichang Xia

Journal Article

Assessment of vaccination strategies against highly pathogenic avian influenza in China

Honglei SUN,Jinhua LIU

Journal Article

Research progress on human infection with avian influenza H7N9

Xiaoxin Wu, Lanlan Xiao, Lanjuan Li

Journal Article

Recent advances in “universal” influenza virus antibodies: the rise of a hidden trimeric interface in

Yulu Wang, Dan Hu, Yanling Wu, Tianlei Ying

Journal Article

Universal influenza virus vaccines: what can we learn from the human immune response following exposure

Daniel Stadlbauer, Raffael Nachbagauer, Philip Meade, Florian Krammer

Journal Article

Seroprevalence of influenza viruses in Shandong, Northern China during the COVID-19 pandemic

Journal Article

Pathogenesis of pandemic H1N1 2009 influenza virus infection and the implication on management

Kelvin Kai-Wang TO FRCPath, Iris Wai-Sum LI FRCP, Ivan Fan-Ngai HUNG FRCP, Vincent Chi-Chung CHENG FRCPath, Kwok-Yung YUEN MD,

Journal Article

Innate and adaptive T cells in influenza disease

Simone Nüssing, Sneha Sant, Marios Koutsakos, Kanta Subbarao, Thi H.O. Nguyen, Katherine Kedzierska

Journal Article

Compiling of comprehensive data of human infections with novel influenza A (H7N9) virus

Ying Wu, George F. Gao

Journal Article

Global influenza surveillancewith Laplacianmultidimensional scaling

Xi-chuan ZHOU,Fang TANG,Qin LI,Sheng-dong HU,Guo-jun LI,Yun-jian JIA,Xin-ke LI,Yu-jie FENG

Journal Article

Removal of virus aerosols by the combination of filtration and UV-C irradiation

Journal Article

Critical roles of chemokines and cytokines in antiviral innate immune responses during rabies virus infection

Ying HUANG, Clement Wesley GNANADURAI, Zhenfang FU

Journal Article

Immunological and virological characteristics of human immunodeficiency virus type 1 superinfection:

Yang Gao, Wen Tian, Xiaoxu Han, Feng Gao

Journal Article